死亡相關蛋白1抗體-分析方法-資訊-生物在線

死亡相關蛋白1抗體

作者:上海雅吉生物科技有限公司 2020-11-05T00:00 (訪問量:3372)

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中文名稱 死亡相關蛋白1抗體
別????名 DAP 1; DAP; DAP-1; DAP1_HUMAN; Death associated protein 1; Death associated protein; Death-associated protein 1.??
研究領域 細胞生物??信號轉導??細胞凋亡??
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,?Rat,? (predicted: Mouse,?Dog,?Pig,?Cow,?Horse,?Sheep,?)
產品應用 ELISA=1:500-1000?IHC-P=1:100-500?IHC-F=1:100-500?IF=1:100-500?(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分?子?量 11kDa
細胞定位 細胞核?細胞漿?
性????狀 Liquid
濃????度 1mg/ml
免?疫?原 KLH conjugated synthetic peptide derived from human DAP1:61-102/102?
亞????型 IgG
純化方法 affinity purified by Protein A
儲?存?液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
產品介紹 his gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma.

Function:
Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.

Post-translational modifications:
Phosphorylated. Phosphorylation by MTOR inhibits the suppressive activity of DAP toward autophagy.

SWISS:
P51397

Gene ID:
1611

Database links:

Entrez Gene: 1611?Human

Entrez Gene: 223453?Mouse

Entrez Gene: 64322?Rat

Omim: 600954?Human

SwissProt: P51397?Human

SwissProt: Q91XC8?Mouse

SwissProt: Q9QX67?Rat

Unigene: 75189?Human

Unigene: 222867?Mouse

Unigene: 1531?Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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產品圖片 Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAP1) Polyclonal Antibody, Unconjugated (bs-6351R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (rat colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAP1) Polyclonal Antibody, Unconjugated (bs-6351R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAP1) Polyclonal Antibody, Unconjugated (bs-6351R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.Paraformaldehyde-fixed, paraffin embedded (rat lung); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (DAP1) Polyclonal Antibody, Unconjugated (bs-6351R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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