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Ras protein is a membrane-associated GTPase signaling protein that regulates proliferation, differentiation, and cell survival. Ras Q61H mutation result in decreased GTPase activ
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NFE2L2 protein is encoded by NFE2L2 gene. It is a basic leucine zipper protein that regulates the expression
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EGFR is a receptor tyrosine kinase binding ligands of the EGF family
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Rab5 is a member of Rab-family GTPases. Rab5 is a rate-limiting component of the machinery regulating the kinetics of membrane traffic in the early endocytic pathway.
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Ras (Q61L) is one type of Ras missence mutations at codon 61,Ras protein is a membrane-associated GTPase signaling protein that regulates proliferation, differentiation,and cell s
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EYA2 may be involved in development of the eye. It promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its
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Ataxia telangiectasia mutated (ATM) is a serine
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Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases
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EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. I
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JAK2 is a non-receptor tyrosine kinase.
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