Recombinant Human SCF Protein,mFc Tag 重組人干細(xì)胞因子
產(chǎn)品名稱： Recombinant Human SCF Protein,mFc Tag 重組人干細(xì)胞因子
英文名稱： Recombinant Human SCF Protein,mFc Tag 重組人干細(xì)胞因子
產(chǎn)品編號(hào)： 94054ES
產(chǎn)品價(jià)格： 詢價(jià)
產(chǎn)品產(chǎn)地： Yeasen
品牌商標(biāo)： Yeasen
更新時(shí)間： 2026-02-10T17:09:30
使用范圍： null
翌圣生物科技（上海）股份有限公司
- 聯(lián)系人 : 李自轉(zhuǎn)
- 地址 : 上海市浦東新區(qū)天雄路166弄一號(hào)樓三層南單元
- 郵編 : 200030
- 所在區(qū)域 : 上海
- 電話 : 139****5640 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
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產(chǎn)品介紹
SCF protein (Stem Cell Factor), also known as Kit Ligand-1 (KL-1), is a multifunctional cytokine protein that plays an important role in biological processes such as cell proliferation, differentiation, and survival. The SCF protein primarily exerts its effects by binding to its receptor c-Kit. c-Kit is a tyrosine kinase receptor that is widely expressed in various cell types. The binding of SCF to c-Kit activates multiple signaling pathways, including PI3K/Akt, MAPK, STAT, etc., thereby regulating cell growth, proliferation, and differentiation.
SCF protein plays a crucial role in the hematopoietic system, particularly in the proliferation and differentiation of stem cells. In diseases, SCF protein also plays a significant role. Aberrant activation of the SCF/c-Kit signaling pathway may lead to the development of certain diseases, such as tumors. Therefore, SCF protein and its receptor c-Kit could potentially serve as therapeutic targets for certain diseases.
產(chǎn)品性質(zhì)
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產(chǎn)品別稱
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KITLG,FPH2,KL-1,Kitl,MGF,SCF,SF,SHEP7,KL
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種屬
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Human
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表達(dá)序列
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Glu 26 - Ala 190
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Accession
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P21583-1
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標(biāo)簽
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C-mFc Tag
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表達(dá)系統(tǒng)
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HEK293
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分子量
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The protein has a predicted MW of 43.9 kDa
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純度
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> 95% as determined by SDS-PAGE
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內(nèi)毒素
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< 1.0 EU per μg by the LAL method.
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制劑
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Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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外觀
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Liquid
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生物活性
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ELISA: Human c-Kit(CD117) Protein; His Tag was immobilized at 2 μg/ml (100 μL/well). Increasing concentrations of Human SCF Protein,mFc Tag were added.
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產(chǎn)品特色
高純度、高活性、低內(nèi)毒素、高批間一致性
應(yīng)用案例
SDS-PAGE
Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Human c-Kit(CD117) Protein; His Tag was immobilized at 2 μg/ml (100 μL/well). Increasing concentrations of Human SCF Protein,mFc Tag were added.
存儲(chǔ)條件
-85 ~ -65℃保存，收到貨之日起，6個(gè)月有效期。避免反復(fù)凍融，建議等分分裝為一次實(shí)驗(yàn)使用量，分裝后，-80℃凍存。