PeproTech重組人GDF-3 (Animal Free) 500ug
產品名稱: PeproTech重組人GDF-3 (Animal Free) 500ug
英文名稱: Recombinant Human GDF-3
產品編號: AF-120-22
產品價格: 0
產品產地: 美國
品牌商標: PeproTech
更新時間: null
使用范圍: null
美國PeproTech(派普泰克)公司中國代表處
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- 地址 :  江蘇省蘇州市工業園區星湖街218號A1北座4樓L03
- 郵編 : 215123
- 所在區域 : 江蘇
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- 郵箱 : peprotech.infochina@thermofisher.com
Recombinant Human GDF-3
Catalog Number:AF-120-22Synonyms:Growth/Differentiation, Factor-3, Vgr-2Description:GDF-3 is a member of the TGF-β superfamily of growth and differentiation factors, and is highly homologous to GDF-9.? Unlike most TGF-β family members, GDF-3 and GDF-9 are not disulfide-linked dimers.? GDF-3 is expressed in adult bone marrow, spleen, thymus, and adipose tissue.? The expression of GDF-3 is upregulated in high-fat-fed wild-type FABP4/aP2 null mice and was associated with obesity, but not with the related hyperglycemia/hyperinsulinemia which characterizes Type 2 diabetes.? Recombinant human GDF-3 is a 26.0 kDa non-disulfide-linked homodimer containing two 114 amino acid polypeptide chains. Manufactured using all non-animal reagents.AA Sequence:AAIPVPKLSC KNLCHRHQLF INFRDLGWHK WIIAPKGFMA NYCHGECPFS LTISLNSSNY AFMQALMHAV DPEIPQAVCI PTKLSPISML YQDNNDNVIL RHYEDMVVDE CGCGSource:E.coliPurity:Greater than 98% by SDS-PAGE gel and HPLC analyses.Biological Activity:Determined by its ability to inhibit induced alkaline phosphatase production by ATDC-5 chondrogenic cells.? The ED50 for this effect is 100-150 ng/ml.????Research Interests:??Country of Origin:USAResearch Use Only. Not for use in diagnostic or therapeutic procedures.
