KCNJ10 Pre-design Chimera RNAi
產(chǎn)品名稱： KCNJ10 Pre-design Chimera RNAi
英文名稱： KCNJ10 Pre-design Chimera RNAi
產(chǎn)品編號(hào)： H00003766-R01
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
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- Specification
- Product Description:
- Homo sapiens potassium inwardly-rectifying channel, subfamily J, member 10 (KCNJ10), mRNA.
- Reactivity:
- Human
- Storage Instruction:
- Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
- Supplied Product:
- DEPC water
- Target Refseq:
- NM_002241
- Note:
- Position of the Chimera RNAi.
-
- Publication Reference
- 1.
- dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference.
Naito Y, Yamada T, Matsumiya T, Ui-Tei K, Saigo K, Morishita S.Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W589-91.
- 2.
- Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly reduced off-target effect.
Ui-Tei K, Naito Y, Zenno S, Nishi K, Yamato K, Takahashi F, Juni A, Saigo K.Nucleic Acids Res. 2008 Apr;36(7):2136-51. Epub 2008 Feb 11.
- 3.
- Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference.
Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A, Ueda R, Saigo K.Nucleic Acids Res. 2004 Feb 9;32(3):936-48. Print 2004.
- 4.
- siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference.
Naito Y, Yamada T, Ui-Tei K, Morishita S, Saigo K.Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W124-9.
- Application Image
- RNAi Knockdown
- Entrez GeneID:
- 3766
- Gene Name:
- KCNJ10
- Gene Alias:
- BIRK-10,KCNJ13-PEN,KIR1.2,KIR4.1
- Gene Description:
- potassium inwardly-rectifying channel, subfamily J, member 10
- Omim ID:
- 602208
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq
- Other Designations:
- ATP-sensitive inward rectifier potassium channel 10,OTTHUMP00000025748,glial ATP-dependent inwardly rectifying potassium channel KIR4.1,inward rectifier K+ channel KIR1.2,inwardly-rectifying potassium channel Kir1.2