Recombinant Cynomolgus BAFF Protein,His Tag
產品名稱： Recombinant Cynomolgus BAFF Protein,His Tag
英文名稱： Recombinant Cynomolgus BAFF Protein,His Tag
產品編號： 94071ES
產品價格： 詢價
產品產地： Yeasen
品牌商標： Yeasen
更新時間： 2026-02-11T13:13:12
使用范圍： null
翌圣生物科技（上海）股份有限公司
- 聯系人 : 李自轉
- 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
- 郵編 : 200030
- 所在區域 : 上海
- 電話 : 139****5640 點擊查看
- 傳真 : 點擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點擊查看
產品介紹
BAFF (B-cell activating factor, also known as TNFSF13B) is an important cytokine that belongs to the tumor necrosis factor superfamily (TNF superfamily). It is crucial for the development, survival, and activation of B cells. BAFF is primarily secreted by plasma cells, dendritic cells, and other immune cells, playing various immunological roles.
BAFF binds to BAFF receptors on the surface of B cells, promoting their maturation and survival, particularly in the maintenance of peripheral B cell populations. BAFF not only affects B cells but can also stimulate T cells in certain contexts, thus participating in the overall regulation of the immune response. Overexpression of BAFF is linked to several autoimmune diseases, including systemic lupus erythematosus (SLE) and rheumatoid arthritis, as it enhances the survival and activation of autoreactive B cells. BAFF plays important roles in the pathogenesis of various infections and tumors.
In summary, BAFF is a key cytokine involved in the regulation of B cell functions and is closely linked to various disease states. Its study aids in developing new therapeutic strategies.
產品性質
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產品別稱
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TNFSF13B,BAFF,BLYS,CD257,DTL,TALL1,THANK,TNFSF20,ZTNF4
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種屬
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Cynomolgus
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表達序列
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Ala134-Leu285
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Accession
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A0A2K5V2X4
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標簽
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N-His Tag
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表達系統
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HEK293
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分子量
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The protein has a predicted MW of 17.4 kDa
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純度
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> 95% as determined by SDS-PAGE
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內毒素
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< 1.0 EU per μg by the LAL method.
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制劑
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Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
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外觀
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Liquid
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生物活性
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ELISA:.Cynomolgus BAFF Protein; His Tag was immobilized at 1 μg/ml (100 μL/well). Increasing concentrations of Anti-BAFF hlgG1 Antibody were added.
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產品特色
高純度、高活性、低內毒素、高批間一致性
應用案例
SDS-PAGE
Figure 1. On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2.Cynomolgus BAFF Protein; His Tag was immobilized at 1 μg/ml (100 μL/well). Increasing concentrations of Anti-BAFF hlgG1 Antibody were added.
存儲條件
-85 ~ -65℃保存，收到貨之日起，6個月有效期。避免反復凍融，建議等分分裝為一次實驗使用量，分裝后，-80℃凍存。