Product name:Natalizumab (?那他珠單抗?)

Catalog No. :?FrdE00016

MW:

Description:Natalizumab is a recombinant, humanized monoclonal antibody,binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1).Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.

Alternative names:Natalizumab

Specificity target name;species:ITGA4/CD49d[Homo sapiens]

Form:?Liquid

Receptor identification:IgG4-kappa

Storage:?Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 °C for frequent use. Store at -20 to -80 °C for twelve months from the date of receipt.

Purity:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Note:?This product is for research use only,not for diagnostic or therapeutic use.