Cd40lg monoclonal antibody, clone MR1
產品名稱： Cd40lg monoclonal antibody, clone MR1
英文名稱： Cd40lg monoclonal antibody, clone MR1
產品編號： MAB3231
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Hamster monoclonal antibody raised against Cd40lg.
- Immunogen:
- Native Cd40lg from mouse Th1 clone D1.6.
- Host:
- Hamster
- Reactivity:
- Mouse
- Specificity:
- CD154 (Mouse CD40 ligand/gp39), Mr 39-KDa.
- Form:
- Liquid
- Isotype:
- IgG
- Storage Buffer:
- In 100 mM BBS, pH 8.2
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- An essential role for gp39, the ligand for CD40, in thymic selection.
Foy TM, Page DM, Waldschmidt TJ, Schoneveld A, Laman JD, Masters SR, Tygrett L, Ledbetter JA, Aruffo A, Claassen E, Xu JC, Flavell RA, Oehen S, Hedrick SM, Noelle RJ.J Exp Med. 1995 Nov 1;182(5):1377-88.
- 2.
- In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39.
Foy TM, Shepherd DM, Durie FH, Aruffo A, Ledbetter JA, Noelle RJ.J Exp Med. 1993 Nov 1;178(5):1567-75.
- 3.
- The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome.
Aruffo A, Farrington M, Hollenbaugh D, Li X, Milatovich A, Nonoyama S, Bajorath J, Grosmaire LS, Stenkamp R, Neubauer M, et al..Cell. 1993 Jan 29;72(2):291-300.
- Applications
- Flow Cytometry
- Partially purified spleen T cells from BALB/c mice were incubated with either hamster IgG or plate-bound Cd3e monoclonal antibody, clone 145-2C11 for 7 hours at 37°C. The cells were then harvested, double-stained with Cd40lg monoclonal antibody, clone MR1 (Cat # MAB3231)-FITC and anti-CD4+8-R-PE, and analyzed by flow cytometry.