CD2AP Antibody
產品名稱： CD2AP Antibody
英文名稱： CD2AP Antibody
產品編號： 251169
產品價格： null
產品產地： 美國
品牌商標： Abbiotec
更新時間： null
使用范圍： E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500
深圳市豪地華拓生物科技有限公司
- 聯系人 :
- 地址 : 深圳市南山創業路中興城5棟518
- 郵編 : 518054
- 所在區域 : 廣東
- 電話 : 132****4656 點擊查看
- 傳真 : 點擊查看
- 郵箱 : order@otwobiotech.com
CD2-associated protein (CD2AP) is an adapter protein between membrane proteins and the actin cytoskeleton. CD2AP plays a role in receptor clustering and cytoskeletal polarity in the junction between T-cells and antigen-presenting cells. CD2AP anchors the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. CD2AP is also required for cytokinesis. Defects in CD2AP are the cause of susceptibility to focal segmental glomerulosclerosis type 3 (FSGS3), a renal pathology defined by the presence of segmental sclerosis in glomeruli and resulting in proteinuria, reduced glomerular filtration rate and edema.