Size??100ug
Cat code??200675
Species Cross-reactivity??H,M
Key Application??WB
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??55kDa
Sensitivity??This antibody detects endogenous levels of BECN1 and does not cross-react with related proteins.
Immunogen??Purified recombinant human BECN1 protein fragments expressed in E.coli.
UniProt Number??Q14457
GeneBank ID??NM_003766.3
Subcellular location??Golgi apparatus ? trans-Golgi network membrane; Peripheral membrane protein.
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername??Coiled-coil myosin-like BCL2-interacting protein
Protein GT197
Gene_symbol??ATG6; VPS30; beclin1 
Summary??Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).
UniPort summary  Function??Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.
Application Images :??
Western blot detection of BECN1 in Mouse brain,A431&Hela cell lysates using BECN1 antibody (1:1000 diluted).
Predicted band size:52KDa.
Observed band size:55KDa