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Other Recombinant Proteins
Recombinant Human NP-1





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		Synonyms :
Neutrophil Peptide-1, alpha Defensin-1, HNP-1, Cryptdin



		Description :
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system.  The α-defensins which include NP-1, NP-2 and NP-3, are distinguished from the β-defensins by the pairing of their three disulfide bonds.  In addition to antimicrobial activity, NP-1 exhibits chemotactic activity on dendritic cells.  NP-1 is expressed as the C-terminal portion of an inactive precursor protein, which also contains a 19 amino acid N-terminal signal sequence and a 45 amino acid polypeptide.  NP-1 contains a six-cysteine motif that forms three intra-molecular disulfide bonds.  Recombinant human NP-1 is a 3.4 kDa protein containing 30 amino acid residues.



		Catalog #:
300-42



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to chemoattract immature dendritic cells using a concentration of 1.0-10.0 ng/ml.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
ACYCRIPACI AGERRYGYCI YQGRLWAFCC 



		PubMed Link :
NP-1+AND+human+AND+defensin


Country of Origin :
USA
















        Size A
5μg
$80?
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        Size B
20μg
$195?
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        Size C
1mg
$3000?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.