Anti-SMAD4 Mouse Monoclonal Antibody-抗體-抗體-生物在線
武漢紐斯特生物技術有限公司
Anti-SMAD4 Mouse Monoclonal Antibody

Anti-SMAD4 Mouse Monoclonal Antibody

商家詢價

產品名稱： Anti-SMAD4 Mouse Monoclonal Antibody

英文名稱： Anti-SMAD4 Mouse Monoclonal Antibody

產品編號： 26453

產品價格： null

產品產地： 美國

品牌商標： NewEastbio

更新時間： null

使用范圍： ELISA, WB, IHC

武漢紐斯特生物技術有限公司
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  • 地址 : 武漢市東湖新技術開發區光谷生物城B3-3棟2-3樓
  • 郵編 : 430074
  • 所在區域 : 湖北
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SMAD4 [26453]
[100ul]		 ?

Catalog Number:??26453
Gene Symbol:??SMAD4, DPC4, JIP, MADH4, MYHRS
Description: ??Anti-SMAD4 Mouse Monoclonal Antibody
Background: ??SMAD4 family member 4, also known as SMAD4, is a protein that in human is encoded by the SMAD4 gene. It is often found mutated in many cancers. It acts as a tumor suppressor that functions in the regulation of the TGF-? signal transduction pathway, which negatively regulates growth of epithelial cells and the extracellular matrix (ECM). SMAD4 alterations have been found in multiploid colorectal cancer and pancreatic carcinoma. It is found inactivated in at least 50% of pancreatic cancers. It is also found mutated in the autosomal dominantdisease juvenile polyposis syndrome (JPS).
Immunogen: ??Purified SMAD4 protein, human origin. .
Applications: ??ELISA, WB, IHC
Recommended Dilutions: ??
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration: ??1 mg/ml
Host: ??Mouse
Format: ??Liquid
Clonality: ??Monoclonal
Isotype: ??
Purity: ??Purified from ascites
Storage buffer:
Preservative:??no
Constituents:??PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:??Recognizes SMAD4 of vertebrates.
Storage Conditions:?? Store at -20°C. Avoid freeze / thaw cycles
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Western blot:??
Western blot analysis of recombinant SMAD4 protein. Purified His-tagged SMAD4 protein (1-552aa, 65kd) and was blotted with anti-SMAD4 monoclonal antibody (Cat. #26453).
Immunofluorescence:??

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Immunofluorescence of cells expressing SMAD4 proteins with anti-SMAD4 antibody. HEK293T cells were transfected with pCDNA3-GFP-SMAD4 (WT) plasmid, then fixed and stained with anti-SMAD4 monoclonal antibody (Cat. #26453).?

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