SHB (Center) Peptide
產(chǎn)品名稱： SHB (Center) Peptide
英文名稱： SHB (Center) Peptide
產(chǎn)品編號： P0370
產(chǎn)品價格： 0
產(chǎn)品產(chǎn)地： 臺灣
品牌商標(biāo)： Abnova
更新時間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
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- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of SHB.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to internal region of human SHB.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:50-100)
Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The SHB adapter protein is required for normal maturation of mesoderm during in vitro differentiation of embryonic stem cells.
Kriz V, Agren N, Lindholm CK, Lenell S, Saldeen J, Mares J, Welsh M.J Biol Chem. 2006 Nov 10;281(45):34484-91. Epub 2006 Sep 12.
- 2.
- SHB and angiogenic factors promote ES cell differentiation to insulin-producing cells.
Saldeen J, Kriz V, Agren N, Welsh M.Biochem Biophys Res Commun. 2006 Jun 2;344(2):517-24. Epub 2006 Apr 19.
- 3.
- Interaction of SH2-Bbeta with RET is involved in signaling of GDNF-induced neurite outgrowth.
Zhang Y, Zhu W, Wang YG, Liu XJ, Jiao L, Liu X, Zhang ZH, Lu CL, He C.J Cell Sci. 2006 Apr 15;119(Pt 8):1666-76. Epub 2006 Mar 28.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of SHB polyclonal antibody (Cat # PAB2488) in CEM cell line lysates (35 ug/lane). SHB (arrow) was detected using the purified polyclonal antibody (1 : 60 dilution).
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SHB polyclonal antibody (Cat # PAB2488) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Entrez GeneID:
- 6461
- Protein Accession#:
- NP_003019;Q15464
- Gene Name:
- SHB
- Gene Alias:
- RP11-3J10.8,bA3J10.2
- Gene Description:
- Src homology 2 domain containing adaptor protein B
- Omim ID:
- 600314
- Gene Ontology:
- Hyperlink
- Other Designations:
- OTTHUMP00000021397,SHB (Src homology 2 domain containing) adaptor protein B,SHB adaptor protein (a Src homology 2 protein)