TRPC6 polyclonal antibody
產品名稱: TRPC6 polyclonal antibody
英文名稱: TRPC6 polyclonal antibody
產品編號: PAB7504
產品價格: null
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍:
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of TRPC6.
- Immunogen:
- A synthetic peptide corresponding to human TRPC6.
- Sequence:
- C-EKLSMEPNQEETN
- Host:
- Goat
- Theoretical MW (kDa):
- 106
- Reactivity:
- Mouse
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:2000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis.
Winn MP, Conlon PJ, Lynn KL, Farrington MK, Creazzo T, Hawkins AF, Daskalakis N, Kwan SY, Ebersviller S, Burchette JL, Pericak-Vance MA, Howell DN, Vance JM, Rosenberg PB.Science. 2005 Jun 17;308(5729):1801-4. Epub 2005 May 5.
- Application Image
- ELISA
- Flow Cytometry
- Entrez GeneID:
- 7225
- Protein Accession#:
- NP_004612.2
- Gene Name:
- TRPC6
- Gene Alias:
- FLJ11098,FLJ14863,FSGS2,TRP6
- Gene Description:
- transient receptor potential cation channel, subfamily C, member 6
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq
- Other Designations:
- transient receptor potential channel 6
