TPR monoclonal antibody (M01), clone 1A8
產品名稱： TPR monoclonal antibody (M01), clone 1A8
英文名稱： TPR monoclonal antibody (M01), clone 1A8
產品編號： H00007175-M01
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant TPR.
- Immunogen:
- TPR (NP_003283, 1 a.a. ~ 98 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MAAVLQQVLERTELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKE
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG1 Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Herpes Simplex Virus Replication: Roles of Viral Proteins and Nucleoporins in Capsid-Nucleus Attachment.
Copeland AM, Newcomb WW, Brown JC.J Virol. 2009 Feb;83(4):1660-8. Epub 2008 Dec 10.
- 2.
- Quantitative Analysis of HIV-1 Infected CD4+ Cell Proteome: Dysregulated Cell Cycle Progression and Nuclear Transport Coincide with Robust Virus Production.
Chan EY, Qian WJ, Diamond DL, Liu T, Gritsenko MA, Monroe ME, Camp DG 2nd, Smith RD, Katze MG.J Virol. 2007 Jul;81(14):7571-83. Epub 2007 May 9.
- Applications
- Western Blot (Recombinant protein)
- Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of monoclonal antibody to TPR on formalin-fixed paraffin-embedded human cerebellum. [antibody concentration 3 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged TPR is approximately 0.1ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 7175
- GeneBank Accession#:
- NM_003292
- Protein Accession#:
- NP_003283
- Gene Name:
- TPR
- Gene Alias:
- -
- Gene Description:
- translocated promoter region (to activated MET oncogene)
- Omim ID:
- 189940
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias. [provided by RefSeq
- Other Designations:
- OTTHUMP00000033584,nuclear pore complex-associated protein TPR,nucleoprotein TPR,tumor potentiating region
- Gene Pathway