Active人ARMET全長蛋白質
產品名稱： Active人ARMET全長蛋白質
英文名稱： Arginine rich mutated in early stage tumors Arginine rich protein Arginine-rich protein ARMET ARMET protein ARP Manf MANF_HUMAN Mesencephali
產品編號： ab206464
產品價格： 0
產品產地： 英國
品牌商標： abcam
更新時間： null
使用范圍： null
- 聯系人 :
- 地址 : 深圳市寶安區西鄉寶民二路賢基大廈4E
- 郵編 :
- 所在區域 : 廣東
- 電話 : 133****4454 點擊查看
- 傳真 : 點擊查看
- 郵箱 : 1484332550@qq.com
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- 性質Recombinant
- 來源CHO
- 氨基酸序列
- AccessionP55145
- 種屬Human
- 序列LRPGDCEVCISYLGRFYQDLKDRDVTFSPATIENELIKFCREARGKENRL CYYIGATDDAATKIINEVSKPLAHHIPVEKICEKLKKKDSQICELKYDKQ IDLSTVDLKKLRVKELKKILDDWGETCKGCAEKSDYIRKINELMPKYAPK AASARTDL
- 分子量18 kDa
- 氨基酸25 to 182
- 額外的序列信息This product is for the mature full length protein. The signal peptide is not included.
技術指標
Our?Abpromise guarantee?covers the use of?ab206464?in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 生物活性
Protein is biologically active. Suitable for cell culture and?in vivo?testing. Human recombinant ARMETL1 has been tested in rat 6-OHDA model of Parkinsons disease and shown neureprotection and neurorestoration. ARMETL1 has also shown neuroprotection in animal models of stroke.
- 應用
SDS-PAGE
Functional Studies
Mass Spectrometry
- 內毒素水平< 1.000?Eu/mg
- 形式Liquid
-
濃度10 μg 濃度為 1 mg/ml?
制備和貯存
- 穩定性和存儲
Shipped on Dry Ice. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
常規信息
-
別名
- Arginine rich mutated in early stage tumors
- Arginine rich protein
- Arginine-rich protein
see all - 功能Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
- 序列相似性Belongs to the ARMET family.
- 結構域The N-terminal region may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response.
- 翻譯后修飾May contain sialic acid residues.
- 細胞定位Secreted.
- Information by UniProt
Active human ARMET full length protein 圖像
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Western blot - Active human ARMET full length protein (ab206464)anti-ARMET polyclonal antibody + ab206464 expressed into the supernatant of CHO cell culture medium -
SDS-PAGE - Active human ARMET full length protein (ab206464)