MME monoclonal antibody, clone MEM-78 (APC)
產品名稱： MME monoclonal antibody, clone MEM-78 (APC)
英文名稱： MME monoclonal antibody, clone MEM-78 (APC)
產品編號： MAB4603
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native MME.
- Immunogen:
- Native purified MME from NALM-6 human pre-B cell line.
- Host:
- Mouse
- Theoretical MW (kDa):
- 100
- Reactivity:
- Human
- Specificity:
- This antibody reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 KDa type II integral membrane protein.
- Form:
- Liquid
- Conjugation:
- APC
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Differential expression of CD10 in prostate cancer and its clinical implication.
Dall'Era MA, True LD, Siegel AF, Porter MP, Sherertz TM, Liu AY.BMC Urol. 2007 Mar 2;7:3.
- 2.
- CD10 expression by fusiform stromal cells in nasopharyngeal carcinoma correlates with tumor progression.
Braham H, Trimeche M, Ziadi S, Mestiri S, Mokni M, Amara K, Hachana M, Sriha B, Korbi S.Virchows Arch. 2006 Aug;449(2):220-4. Epub 2006 May 4.
- 3.
- Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74).
Horejsi V, Angelisova P, Bazil V, Kristofova H, Stoyanov S, Stefanova I, Hausner P, Vosecky M, Hilgert I.Folia Biol (Praha). 1988;34(1):23-34.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 4311
- Gene Name:
- MME
- Gene Alias:
- CALLA,CD10,DKFZp686O16152,MGC126681,MGC126707,NEP
- Gene Description:
- membrane metallo-endopeptidase
- Omim ID:
- 120520
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq
- Other Designations:
- atriopeptidase,common acute lymphocytic leukemia antigen,enkephalinase,membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase),membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10),membrane metallo-endopeptidase