ABCA4 polyclonal antibody (A01)
產(chǎn)品名稱： ABCA4 polyclonal antibody (A01)
英文名稱： ABCA4 polyclonal antibody (A01)
產(chǎn)品編號(hào)： H00000024-A01
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a partial recombinant ABCA4.
- Immunogen:
- ABCA4 (NP_000341, 2174 a.a. ~ 2273 a.a) partial recombinant protein with GST tag.
- Sequence:
- PKDDLLPDLNPVEQFFQGNFPGSVQRERHYNMLQFQVSSSSLARIFQLLLSHKDSLLIEEYSVTQTTLDQVFVNFAKQQTESHDLPLHPRAAGASRQAQD
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- 50 % glycerol
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- ABCA4 polyclonal antibody (A01), Lot # 051109JC01 Western Blot analysis of ABCA4 expression in SJCRH30 ( Cat # L027V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Entrez GeneID:
- 24
- GeneBank Accession#:
- NM_000350
- Protein Accession#:
- NP_000341
- Gene Name:
- ABCA4
- Gene Alias:
- ABC10,ABCR,ARMD2,CORD3,DKFZp781N1972,FFM,FLJ17534,RMP,RP19,STGD,STGD1
- Gene Description:
- ATP-binding cassette, sub-family A (ABC1), member 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq
- Other Designations:
- ATP binding cassette transporter,ATP-binding cassette, sub-family A member 4,ATP-binding transporter, retina-specific,OTTHUMP00000012366,photoreceptor rim protein,retina-specific ABC transporter
- Gene Pathway
- Related Disease
- Atherosclerosis
- Blindness
- Calcinosis
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Coronary Artery Disease
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Kidney Failure, Chronic
- Macular Degeneration
- Retinal Degeneration
- Retinal Diseases
- Retinitis Pigmentosa
- Tobacco Use Disorder