Anti-TRAF3 Monoclonal Antibody
產(chǎn)品名稱： Anti-TRAF3 Monoclonal Antibody
英文名稱： TRAF3
產(chǎn)品編號(hào)： K001592M
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 北京
品牌商標(biāo)： Solarbio
更新時(shí)間： null
使用范圍： WB IF
北京索萊寶科技有限公司--實(shí)驗(yàn)室產(chǎn)品
- 聯(lián)系人 :
- 地址 : 北京市通州區(qū)馬駒橋聯(lián)東U谷景盛南四街85A三層
- 郵編 :
- 所在區(qū)域 : 北京
- 電話 : 010-563*1250 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : 2748554845@qq.com
TNF receptor-associated factor 3 (TRAF3) has many alternative names including CAP-1 CD40 receptor-associated factor 1(CRAF1) CD40-binding protein(CD40BP) and LMP1-associated protein 1 (LAP1). TRAF3 regulates pathways leading to the activation of NF-kappa-B and MAP kinases and plays a central role in the regulation of innate immune response. It modulates signaling pathways leading to the production of cytokines and interferon. As an essential constituent of several E3 ubiquitin-protein ligase complexes TRAF3 promote 'Lys-63'-linked ubiquitination of target proteins. Moreover TRAF3 undergoes both 'Lys-48'-linked and 'Lys-63'-linked ubiquitination in response to various stimuli and is deubiquitinated by OTUB1 OTUB2 and OTUD5.