ROCK1 (Human) Recombinant Protein (Q01)
產品名稱: ROCK1 (Human) Recombinant Protein (Q01)
英文名稱: ROCK1 (Human) Recombinant Protein (Q01)
產品編號: H00006093-Q01
產品價格: 0
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍: null
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human ROCK1 partial ORF ( NP_005397, 401 a.a. - 510 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SNRRYLSSANPNDNRTSSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRR
- Theoretical MW (kDa):
- 37.84
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.

- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 6093
- GeneBank Accession#:
- NM_005406
- Protein Accession#:
- NP_005397
- Gene Name:
- ROCK1
- Gene Alias:
- MGC131603,MGC43611,P160ROCK,PRO0435
- Gene Description:
- Rho-associated, coiled-coil containing protein kinase 1
- Omim ID:
- 601702
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq
- Other Designations:
- OTTHUMP00000162514,p160-ROCK
- Related Disease
- Adenocarcinoma
- Cardiovascular Diseases
- Diabetes Mellitus, Type 2
- Edema
- Genetic Predisposition to Disease
- HIV Infections
- Obesity
- Ovarian Failure, Premature
- Pancreatic Neoplasms
- Polycystic Ovary Syndrome
- Puberty, Delayed
- Puberty, Precocious
- Schizophrenia
- Schizophrenia
- Thrombophilia
- Tobacco Use Disorder
