ILK (phospho T173) polyclonal antibody
產品名稱： ILK (phospho T173) polyclonal antibody
英文名稱： ILK (phospho T173) polyclonal antibody
產品編號： PAB1640
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of ILK.
- Immunogen:
- Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T173 of human ILK.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein A purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis.
Li Y, Yang J, Dai C, Wu C, Liu Y.J Clin Invest. 2003 Aug;112(4):503-16.
- 2.
- Characterisation of integrin-linked kinase signalling in sporadic human colon cancer.
Marotta A, Parhar K, Owen D, Dedhar S, Salh B.Br J Cancer. 2003 Jun 2;88(11):1755-62.
- 3.
- Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation.
Troussard AA, Mawji NM, Ong C, Mui A, St -Arnaud R, Dedhar S.J Biol Chem. 2003 Jun 20;278(25):22374-8. Epub 2003 Apr 8.
- Entrez GeneID:
- 3611
- Protein Accession#:
- Q13418;NP_004508
- Gene Name:
- ILK
- Gene Alias:
- DKFZp686F1765,P59
- Gene Description:
- integrin-linked kinase
- Omim ID:
- 602366
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- -