TLR5 monoclonal antibody (M10), clone 4D12
產品名稱： TLR5 monoclonal antibody (M10), clone 4D12
英文名稱： TLR5 monoclonal antibody (M10), clone 4D12
產品編號： H00007100-M10
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant TLR5.
- Immunogen:
- TLR5 (NP_003259.2, 351 a.a. ~ 450 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- LYSSNFYGLPKVAYIDLQKNHIAIIQDQTFKFLEKLQTLDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHL
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
Download
- Applications
- Western Blot (Cell lysate)
- TLR5 monoclonal antibody (M10), clone 4D12. Western Blot analysis of TLR5 expression in FHs 173 WE.
- Protocol Download
- Entrez GeneID:
- 7100
- GeneBank Accession#:
- NM_003268
- Protein Accession#:
- NP_003259.2
- Gene Name:
- TLR5
- Gene Alias:
- FLJ10052,MGC126430,MGC126431,SLEB1,TIL3
- Gene Description:
- toll-like receptor 5
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene product is expressed in myelomonocytic cells, and recognizes bacterial flagellin, a principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB and stimulates tumour necrosis factor-alpha production. [provided by RefSeq
- Other Designations:
- OTTHUMP00000036039,Toll/interleukin-1 receptor-like protein 3
- Related Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Bacteriuria
- Bronchiolitis Obliterans
- Bronchiolitis, Viral
- Cardiovascular Diseases
- Chagas Cardiomyopathy
- Chorioamnionitis
- Chronic Disease
- Crohn Disease
- Crohn's disease
- Cystic Fibrosis
- Cystitis
- Diabetes Mellitus, Type 2
- Disease Susceptibility
- Duodenal Ulcer
- Edema
- Fetal Membranes, Premature Rupture