Anti-ATIC
產(chǎn)品名稱： Anti-ATIC
英文名稱：
產(chǎn)品編號： 200668
產(chǎn)品價格： null
產(chǎn)品產(chǎn)地： 成都正能生物
品牌商標： Zen BioScience
更新時間： null
使用范圍： WB
- 聯(lián)系人 :
- 地址 : 中國成都高新區(qū)科園南路愛斯特大廈
- 郵編 : 610200
- 所在區(qū)域 : 四川
- 電話 : 180****2350 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@zen-bioscience.com
Size??100ug
Cat code??200668
Species Cross-reactivity??H,M,R
Key Application??WB
Host??Mouse
Antibody type??Monoclonal antibody
Purified method??Affinity purified
Isotype??IgG1
Molecular Weight??64kDa
Sensitivity??This antibody detects endogenous levels of ATIC and does not cross-react with related proteins.
Immunogen??Purified recombinant human ATIC protein fragments expressed in E.coli.
UniProt Number??P31939
GeneBank ID??NM_004044.6
Subcellular location??null
Formulation??Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Altername??5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase,AICAR transformylase2.IMP cyclohydrolase,ATIC,IMP synthase Inosinicase
Gene_symbol??PURH; AICAR; AICARFT; IMPCHASE
Summary??This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria.
UniPort summary Function??Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis.
Application Images :??
Western blot detection of ATIC in various tissue and cell lysates using ATIC antibody (1:1000 diluted). Predicted band size:64KDa. Observed band size:64KDa
