Recombinant Human BD-3
產品名稱： Recombinant Human BD-3
英文名稱： Recombinant Human BD-3
產品編號： 300-52
產品價格： 0
產品產地： USA
品牌商標： PEPROTECH
更新時間： null
使用范圍： null
上海研卉生物科技有限公司
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產品編號:
300-52
別名:
beta-defensin-3, DEFB3, DEFB103A
描述:
Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human BD-3 is a 5.1 kDa protein containing 45 amino acid residues.
氨基酸序列:
GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Exhibits antimicrobial activity against gram-positive bacteria S. aureus and gram-negative P. aeruginosa and E.coli.
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交叉反應:
Bacteria, Mouse, Virus
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原產國:
USA
僅用于研究。不適用于診斷或治療。