DMD(Texas Red)/CENXp(FITC) FISH Probe
產(chǎn)品名稱： DMD(Texas Red)/CENXp(FITC) FISH Probe
英文名稱： DMD(Texas Red)/CENXp(FITC) FISH Probe
產(chǎn)品編號： FA0616
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 臺灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍： null
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺灣臺北市內(nèi)湖區(qū)洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Entrez GeneID:
- 1756
- Gene Name:
- DMD
- Gene Alias:
- BMD,CMD3B,DXS142,DXS164,DXS206,DXS230,DXS239,DXS268,DXS269,DXS270,DXS272
- Gene Description:
- dystrophin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The dystrophin gene is the largest gene found in nature, measuring 2.4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X-linked disorder occurring at a frequency of about 1 in 3,500 new-born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature translation termination (nonsense or frame shift mutations), while in BMD patients dystrophin is reduced either in molecular weight (derived from in-frame deletions) or in expression level. The dystrophin gene is highly complex, containing at least eight independent, tissue-specific promoters and two polyA-addition sites. Furthermore, dystrophin RNA is differentially spliced, producing a range of different transcripts, encoding a large set of protein isoforms. Dystrophin (as encoded by the Dp427 transcripts) is a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers. Dystrophin is part of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton (F-actin) and the extra-cellular matrix. [provided by RefSeq
- Other Designations:
- Duchenne muscular dystrophy protein,OTTHUMP00000023117,OTTHUMP00000023124,OTTHUMP00000023125,OTTHUMP00000023126,muscular dystrophy, Duchenne and Becker types
- Related Disease
- Bone Marrow Diseases
- Cardiomyopathy, Dilated
- Cardiovascular Diseases
- Cognition
- Cognition Disorders
- Diabetes Mellitus, Type 2
- Duchenne muscular dystrophy
- Edema
- Genetic Predisposition to Disease
- Intelligence Tests
- Mental Retardation
- Muscular Dystrophies
- Muscular Dystrophy, Duchenne
- Neuropsychological Tests
- Ventricular Dysfunction, Left