F8 monoclonal antibody
產品名稱： F8 monoclonal antibody
英文名稱： F8 monoclonal antibody
產品編號： MAB2175
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native F8.
- Immunogen:
- Native purified human F8.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- Recognize full-length human Factor VIII.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Native Purified Protein.
- Recommend Usage:
- ELISA (1:16000)
The optimal working dilution should be determined by the end user.
- Application Image
- ELISA
- Entrez GeneID:
- 2157
- Gene Name:
- F8
- Gene Alias:
- AHF,DXS1253E,F8B,F8C,FVIII,HEMA
- Gene Description:
- coagulation factor VIII, procoagulant component
- Omim ID:
- 306700
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq
- Other Designations:
- OTTHUMP00000061446,OTTHUMP00000196174,coagulation factor VIII,coagulation factor VIIIc,factor VIII F8B,procoagulant component
- Interactome
- Gene Pathway
- Related Disease
- Abortion, Habitual
- Activated Protein C Resistance
- Anemia, Sickle Cell
- Anemia, sickle cell
- Arteriosclerosis
- Atherosclerosis
- Autoimmune Diseases
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Cerebrovascular Disorders
- Chromosome Inversion
- Coronary Disease
- Diabetes Mellitus
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Fetal Growth Retardation
- Genetic Predisposition to Disease
- Hemophilia A