NOD2 polyclonal antibody
產品名稱： NOD2 polyclonal antibody
英文名稱： NOD2 polyclonal antibody
產品編號： PAB14577
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of NOD2.
- Immunogen:
- A synthetic peptide corresponding to amino acids 125-140 of human NOD2.
- Sequence:
- PHSLHPARDLQSHRPA
- Host:
- Rabbit
- Reactivity:
- Bison, Bovine, Human, Monkey, Mouse, Rat
- Specificity:
- Nod2 antibody will cross-react with mouse, based on NCBI BLAST
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.05% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- CARD15 gene and the classification of Crohn's disease.
Murillo L, Crusius JB, van Bodegraven AA, Alizadeh BZ, Pena AS.Immunogenetics. 2002 Apr;54(1):59-61. Epub 2002 Mar 2.
- 2.
- Nods: a family of cytosolic proteins that regulate the host response to pathogens.
Inohara N, Ogura Y, Nunez G.Curr Opin Microbiol. 2002 Feb;5(1):76-80.
- 3.
- CARD15 mutations in Blau syndrome.
Miceli-Richard C, Lesage S, Rybojad M, Prieur AM, Manouvrier-Hanu S, Hafner R, Chamaillard M, Zouali H, Thomas G, Hugot JP.Nat Genet. 2001 Sep;29(1):19-20.
- Application Image
- ELISA
- Entrez GeneID:
- 64127
- Protein Accession#:
- NP_071445;NP_071445.1
- Gene Name:
- NOD2
- Gene Alias:
- ACUG,BLAU,CARD15,CD,CLR16.3,IBD1,NLRC2,NOD2B,PSORAS1
- Gene Description:
- nucleotide-binding oligomerization domain containing 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq
- Other Designations:
- NLR family, CARD domain containing 2,NOD-like receptor C2,OTTHUMP00000164224,caspase recruitment domain family, member 15,caspase recruitment domain protein 15,inflammatory bowel disease protein 1,nucleotide-binding oligomerization domain 2,nucleotide-bin
- Related Disease
- Abscess
- Acquired Hyperostosis Syndrome
- Acute Disease
- Adenocarcinoma
- Anus Diseases
- Arthritis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Arthropathy, Neurogenic
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation
- Autoimmune Diseases
- Bacteremia
- Bacterial Infections
- Behcet Syndrome