AANAT Rabbit pAb (APR21565N)
產品名稱: AANAT Rabbit pAb (APR21565N)
英文名稱: AANAT Rabbit pAb (APR21565N)
產品編號: APR21565N
產品價格: null
產品產地: 美國
品牌商標: Leading Biology
更新時間: null
使用范圍:
分子量:Calculated MW: 23kDa/28kDa 細胞定位:Cytoplasm 稀釋方法:IF 1:50 - 1:200 總結:The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
