分子量：Calculated MW: 43kDa
Observed MW: Refer to figures

細胞定位：Cell junction, Cell membrane, Endoplasmic reticulum, Multi-pass membrane protein, gap junction

稀釋方法：IHC 1:50 - 1:200

總結：This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations.