目錄號 
                        
規格 
                        
價格 
                        
說明書下載 
                    
                    

                        
C644A
                        
2μg
                        
400元
                        

                    
                    

                        
C644B
                        
10μg
                        
1800元
                    
                    

                        
C644C
                        
50μg
                        
4500元
                    
                
            
            
        
        

            

            
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Kunitz-type protease inhibitor 2 , also known as HAI-2 , SPINT2 and KOP, is a Kunitz-type serine protease inhibitor. SPINT2 is a single-pass type I membrane protein and contains two BPTI/Kunitz inhibitor domains. the first Kunitz domain is mainly responsible for the inhibitory activity against hepatocyte growth factor activator (HGFA). SPINT2 is expressed in placenta, kidney, pancreas, prostate, testis, thymus and trachea. SPINT2 serves as a inhibitor of HGF activator. It also inhibits plasmin, plasma and tissue kallikrein and factor XIa. Defects in SPINT2 are the cause of diarrhea type 3 (DIAR3), also known as congenital sodium diarrhea (CSD).
            


            ·Description

            Novoprotein Recombinant Human HAI-2 produced by mammalian cells expression system.Target protein is expressed with sequence (Ala28-Lys197) of Human hai-2 (Uniprot #O43291) fused with a polyhistidine tag at the C-terminus.
            


            ·Quality Control
            
Purity: Greater than 90.0% as determined by: 

            (a) Analysis by RP-HPLC. 

            (b) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel. 

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Endotoxin:Less than 0.1ng/μg (1EU/μg) of HAI-2 (Human)
            
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·Formulation

            ? Novoprotein Recombinant Human SPINT2 was lyophilized at 1mg/ml in 20mM PBS.
            
·Reconstitution

            We recommend a quick spin followed by reconstitution of Novoprotein Recombinant Human SPINT2 in sterile 18MΩ-cm H2O not less than 100μg/ml, which can then be further diluted to working solutions.
            
·Storage 

            Lyophilized Recombinant Human SPINT2 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Recombinant Human SPINT2 should be stored at 4°C between 2-7 days and aliquots of reconstituted samples are stable up to 3 months below -18°C for future use.
            
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Please avoid freeze-thaw cycles.