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?英文名稱 Dopamine Receptor D1?
中文名稱 多巴胺受體D1重組兔單克隆抗體?
別? ? 名 DRD1; dopamine D1 receptor; D(1A) dopamine receptor; D1A dopamine receptor; Dopamine D1Receptors; D1DR; DADR; Dopamine Receptor D1; DR D1; DR D1A; DRD 1; DRD1 receptor; DRD1; DRD1A; DRD1_HUMAN; D(1A) dopamine receptor; DRD 1A; DRD1.? ?
研究領域 腫瘤? 免疫學? 神經生物學? ?
抗體來源 Rabbit?
克隆類型 Monoclonal?
克 隆 號 3C3?
交叉反應 (predicted: Human, Mouse, Rat, )?
產品應用 WB=1:500-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:100-500 IF=1:50-200 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.?
分 子 量 50kDa?
細胞定位 細胞漿 細胞膜??
性? ? 狀 Liquid?
濃? ? 度 1mg/ml?
免 疫 原 C-terminus human Dopamine Receptor D1:??
亞? ? 型 IgG?
純化方法 affinity purified by Protein A?
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.?
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.?
PubMed PubMed?
產品介紹 This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]
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Function:
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
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Subunit:
Interacts with DNAJC14 via its C-terminus. Interacts with DRD1IP.
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Subcellular Location:
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
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Tissue Specificity:
Detected in caudate, nucleus accumbens and in the olfactory tubercle.
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Similarity:
Belongs to the G-protein coupled receptor 1 family.
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SWISS:
P21728
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Gene ID:
1812
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Database links:
Entrez Gene: 1812 HumanEntrez Gene: 13488 MouseEntrez Gene: 24316 RatOmim: 126449 HumanSwissProt