Anti-AGO1 Polyclonal Antibody
產品名稱: Anti-AGO1 Polyclonal Antibody
英文名稱: EIF2C;EIF2C1;GERP95;Q99;hAgo1
產品編號: K004319P
產品價格: null
產品產地: 北京
品牌商標: Solarbio
更新時間: null
使用范圍: WB
北京索萊寶科技有限公司--實驗室產品
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- 所在區域 : 北京
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This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.
