PARK2 (phospho S378) polyclonal antibody-抗體-抗體-生物在線

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亞諾法生技股份有限公司（Abnova)
PARK2 (phospho S378) polyclonal antibody

PARK2 (phospho S378) polyclonal antibody

商家詢價

產品名稱： PARK2 (phospho S378) polyclonal antibody

英文名稱： PARK2 (phospho S378) polyclonal antibody

產品編號： PAB9602

產品價格： null

產品產地： 臺灣

品牌商標： Abnova

更新時間： null

使用范圍：

亞諾法生技股份有限公司（Abnova)
  • 聯系人 :
  • 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
  • 郵編 : 11493
  • 所在區域 : 臺灣
  • 電話 : +886-920**1152 點擊查看
  • 傳真 : 點擊查看
  • 郵箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic phosphopeptide of PARK2.
  • Immunogen:
  • Synthetic phosphopeptide corresponding to residues surrounding S378 of human PARK2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 52
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Storage Buffer:
  • In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Publication Reference
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot of HEK293 cells transfected with PARK2 WT (Phospho) and PARK2 S378 mutant (non-phospho) showing the phospho-specific immunolabeling of the ~ 52 k parkin protein. The immunolabeling is absent in the PARK2 S378 mutant.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5071
  • Gene Name:
  • PARK2
  • Gene Alias:
  • AR-JP,LPRS2,PDJ,PRKN
  • Gene Description:
  • Parkinson disease (autosomal recessive, juvenile) 2, parkin
  • Gene Summary:
  • The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq
  • Other Designations:
  • E3 ubiquitin ligase,OTTHUMP00000017565,OTTHUMP00000017566,OTTHUMP00000017567,parkin,parkin 2
  • Interactome

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