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VCU動物顱腦損傷儀

VCU動物顱腦損傷儀可以分為細(xì)胞顱腦損傷儀(CIC)，電子顱腦損傷儀(eCCI)及液壓顱腦損傷儀(FPI)，這三種產(chǎn)品己廣泛應(yīng)用于世界范圍內(nèi)的顱腦創(chuàng)傷研究中心，是目前唯一的顱腦創(chuàng)傷模型制作的金標(biāo)準(zhǔn)。

電子顱腦損傷儀(eCCI)

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細(xì)胞顱腦損傷儀(CIC) ??????，???

液壓顱腦損傷儀(FPI)

液壓顱腦損傷儀(FPI)

液壓顱腦損傷儀(FPI)是由VCU 大學(xué)所制作設(shè)計(jì)的，針對神經(jīng)創(chuàng)傷機(jī)制研究，成為全球研究神經(jīng)創(chuàng)傷廣泛使用的儀器，基本的組件是採取最先進(jìn)的power coating process技術(shù)，鋁制部分的組件都已經(jīng)電度以避免氧化且可以長久使用。

The FPI is constructed with a sturdy aluminum frame and the basic structure is finished with a state-of-the-art powder coating process. The balance of the aluminum components are anodized to prevent oxidation and guarantee longevity.

FPI assembly includes the base pendulum mast, graduated protractor, ball bearing-enhanced impact hammer assembly, acrylic fluid cylinder and bracketry, transducer housing, transfer tube and a digital transducer. The device is completed with a self-calibrating Trauma Inducer Pressure Inducer Amplifier.

電子顱腦損傷儀(eCCI)是由VCU 大學(xué)所制作設(shè)計(jì)的，針對顱腦創(chuàng)傷機(jī)制研究。

電子顱腦損傷儀(eCCI)的組件有: sturdy aluminum frame, animal platform, controller and impactor head。Animal plateform可以和各種的立體定位儀搭配。是藉由controller來控制撞擊的速度，撞擊頭的組件部份有含感應(yīng)器，可以決定速率、撞擊深度及撞擊位置。

The eCCI is constructed with a sturdy aluminum frame to maximize rigidity, thereby ensuring impact accuracy. The support base, animal platform and impactor head are anodized to prevent oxidation and assure equipment longevity.??

Product assembly includes the base and support frame, and adjustable animal positioner with an aluminum animal platform to be used in conjunction with a variety of stereotactic mounts. This model utilizes the enhanced linier motor driven impactor and controller. The enhanced impact head also houses a photo-optic sensor to determine velocity, impact depth and dwell, and is extremely reproducible.

細(xì)胞顱腦損傷儀(CIC)

細(xì)胞損傷控制儀(CI採取電子式控制，適合morphologic、病理理及培養(yǎng)組織損傷后的機(jī)制、形態(tài)學(xué)、病理性。細(xì)胞損傷控制儀是針對Flexcell Int’l corp具有專利的tissue culture system。細(xì)胞損傷控制儀平均把壓縮氣體送到每個culture wells，以造成培養(yǎng)組織牽張性的損傷，損傷的嚴(yán)重程度是依據(jù)氣體在密閉的culture well進(jìn)出的量，細(xì)胞損傷控制儀(CIC)是可以搭配Flex ? 29.45cm2 culturing trays I (針對VCU早期的細(xì)胞損傷控制儀)和BioFlex? 57.75cm2 culturing trays。因為根據(jù)所採用的細(xì)胞種類、損傷的程度、培養(yǎng)的狀況，受損后的細(xì)胞或許會因為上述因素死掉或要修護(hù)，所以VCU的細(xì)胞損傷控制儀(CIC)很適合應(yīng)用在下列領(lǐng)域:細(xì)胞受損、修護(hù)，死亡，藥物介入的反應(yīng)。

The Cell Injury Controller II is an electronically controlled pneumatic device that allows the study of morphologic, physiologic and biochemical responses of tissue-cultured cells to trauma.

Depending on the cell type, the degree of injury and the culture conditions, the injured cells may die or repair. Therefore, the system can be employed to study the responses to trauma, including cell injury, repair, death or pharmacologic intervention.

The CIC II has been designed for use with a patented, commercially available tissue culture system from Flexcell International Corp. in Hillsborough, N.C. Tissue cultures are grown in culturing wells with stretchable Silastic? membrane bottoms. The CIC II regulates the flow of compressed gas to rapidly pressurize individual culture wells, causing a radial stretch injury to the culture. Injury severity is determined by controlling the flow of gas in and out of the sealed culture well and the peak pressure is captured to provide an accurate indicator of radial stretch.

The CIC II accepts both the Flex I? 29.45cm2 culturing trays, which were used with the earlier CIC Model 94A, and the BioFlex? 57.75cm2 culturing trays.