Anti-MDM2 Polyclonal Antibody
產(chǎn)品名稱: Anti-MDM2 Polyclonal Antibody
英文名稱: Anti-MDM2 Polyclonal Antibody
產(chǎn)品編號: K106576P
產(chǎn)品價格: null
產(chǎn)品產(chǎn)地: 北京
品牌商標(biāo): solarbio
更新時間: 2026-07-02T10:39:01
使用范圍: WB
北京索萊寶科技有限公司
- 聯(lián)系人 : 索萊寶-龔思雨
- 地址 : 北京市北京經(jīng)濟技術(shù)開發(fā)區(qū)環(huán)科中路16號26幢3層301
- 郵編 :
- 所在區(qū)域 : 北京
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Anti-MDM2 Polyclonal Antibody
品牌:solarbio | 貨號:K106576P
| 英文名稱 | Anti-MDM2 Polyclonal Antibody |
|---|---|
| 別名 | ACTFS;hdm2;HDMX;E3 ubiquitin-protein ligase Mdm2 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 48kDa |
| Gene ID | 4193 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human MDM2 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human MDM2 |
| Subcellular Locations | Nucleus |
| Swiss Prot | Q00987 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Inhibits TP53/p53- and TP73/p73-mediated cell cyclearrest and apoptosis by binding its transcriptional activation domain. Functions as a ubiquitin ligase E3, in the presence of E1 and E2, toward p53 and itself. Permits the nuclear export of p53 and targets it for proteasome-mediated proteolysis. Binds p53, p73, ARF(P14), ribosomal protein L5 and specifically to RNA. Can interact also with retinoblastoma protein(RB), E1A-associated protein EP300 and the E2F1 transcription factor. Forms a ternary complex with TP53/p53 and WWOX. |
