Recombinant Human IL-1RA
產(chǎn)品名稱： Recombinant Human IL-1RA
英文名稱：
產(chǎn)品編號(hào)： C033
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 中國
品牌商標(biāo)： Novoprotein
更新時(shí)間： null
使用范圍： null
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Interleukin-1 Receptor Antagonist (IL-1RN) is a member of the IL-1 family. Endogenous IL-1RN is produced in numerous animal disease models as well as in human autoimmune and chronic inflammatory diseases. It binds to IL-1 receptors in competition with IL-1, but does not elicit intracellular response from this binding. Its role in counteracting the proinflammatory effects of IL-1 is being studied by numerous research groups. IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL-1RN. The regulated expression of IL-1RN in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts, IL-1, TNF-alpha, or PDGF markedly enhances the synthesis of IL-1RN.