CD28 monoclonal antibody, clone CD28.2 (PE)
產品名稱： CD28 monoclonal antibody, clone CD28.2 (PE)
英文名稱： CD28 monoclonal antibody, clone CD28.2 (PE)
產品編號： MAB6487
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against CD28.
- Immunogen:
- Native purified CD28 from DC28.1.3.3 hybridoma cells.
- Host:
- Mouse
- Theoretical MW (kDa):
- 44
- Reactivity:
- Human, Non-Human Primates
- Specificity:
- This antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of MW 44 KDa) which is a critical costimulatory receptor of T cells.
- Form:
- Liquid
- Conjugation:
- PE
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates.
Jeong SH, Qiao M, Nascimbeni M, Hu Z, Rehermann B, Murthy K, Liang TJ.J Virol. 2004 Jul;78(13):6995-7003.
- 2.
- Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling.
Scharschmidt E, Wegener E, Heissmeyer V, Rao A, Krappmann D.Mol Cell Biol. 2004 May;24(9):3860-73.
- 3.
- Negative-feedback regulation of CD28 costimulation by a novel mitogen-activated protein kinase phosphatase, MKP6.
Marti F, Krause A, Post NH, Lyddane C, Dupont B, Sadelain M, King PD.J Immunol. 2001 Jan 1;166(1):197-206.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 940
- Gene Name:
- CD28
- Gene Alias:
- MGC138290,Tp44
- Gene Description:
- CD28 molecule
- Omim ID:
- 186760
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD28 costimulation is essential for CD4 (MIM 186940)-positive T-cell proliferation, survival, interleukin-2 (IL2; MIM 147680) production, and T-helper type-2 (Th2) development.[supplied by OMIM
- Other Designations:
- CD28 antigen,CD28 antigen (Tp44),T-cell-specific surface glycoprotein
- Related Disease
- Acute Disease
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Behcet Syndrome
- Bronchiolitis, Viral
- Carcinoma, Squamous Cell
- Celiac Disease
- Cholangitis, Sclerosing
- Colon cancer
- Colorectal Neoplasms
- Diabetes Mellitus, Type 1
- Disease Progression
- Drug Eruptions
- Genetic Predisposition to Disease
- Hematologic Diseases
- Hepatitis C
- Hodgkin Disease
- Hypersensitivity, Immediate