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Human, Murine & Rat Neurotrophins
Recombinant Human NT-4





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		Synonyms :
Neurotrophin-4, Neurotrophic 4/5 (NT-4/NT-5)



		Description :
NT-4 is a neurotrophic factor structurally related to β-NGF, BDNF, and NT-3.  These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures.  NT-4 is expressed in the prostate, thymus, placenta and skeletal muscle.  NT-4 can signal through the LNGFR and trkB receptors and promotes the survival of peripheral sensory sympathetic neurons.  Recombinant human NT-4 is a noncovalently linked homodimer, of two 14.0 kDa polypeptide monomers (260 total amino acid residues).



		Catalog #:
450-04



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
GVSETAPASR RGELAVCDAV SGWVTDRRTA VDLRGREVEV LGEVPAAGGS PLRQYFFETR CKADNAEEGG PGAGGGGCRG VDRRHWVSEC KAKQSYVRAL TADAQGRVGW RWIRIDTACV CTLLSRTGRA 



		PubMed Link :
Neurotrophin-4+AND+human


Country of Origin :
USA
















        Size A
2μg
$80?
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        Size B
10μg
$195?
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        Size C
1mg
$5200?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.