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Human, Murine & Rat Chemokines
Recombinant Murine MDC (CCL22)





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		Synonyms :
Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1



		Description :
MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells.  It signals through the CCR4 receptor.  MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity.  The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity.  Recombinant murine MDC is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.



		Catalog #:
250-23



		Source :
E.coli



		Purity :
Greater than 98% by SDS-PAGE gel and HPLC analyses.



		Endotoxin Level :
Endotoxin level is less than 0.1 ng per μg (1EU/μg).



		Biological Activity :
Determined by its ability to chemoattract human activated lymphocytes using a concentration of 10.0-100.0 ng/ml.


Selected References :
Selected List of References Citing This PeproTech Product



                AA Sequence :
GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS 



		PubMed Link :
MDC-1+AND+mouse


Country of Origin :
USA
















        Size A
5μg
$80?
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        Size B
20μg
$195?
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        Size C
1mg
$3000?
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Special 
                    Sizes: 
 Many products can be ordered in custom sizes. Please click here to contact Peprotech with your request.





Usage:
For Research Use Only.  Not for use in diagnostic or therapeutic procedures.