Protein Tyrosine Nitration Control (Nitrotyrosine-BSA)
產品名稱： Protein Tyrosine Nitration Control (Nitrotyrosine-BSA)
英文名稱： Protein Tyrosine Nitration Control (Nitrotyrosine-BSA)
產品編號： STA-304
產品價格： 詢價
產品產地： USA
品牌商標： cellbiolabs
更新時間： 2024-12-10T13:18:22
使用范圍：
- 聯系人 : 李自轉
- 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
- 郵編 : 200030
- 所在區域 : 上海
- 電話 : 139****5640 點擊查看
- 傳真 : 點擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點擊查看
Background
Nitric oxide (NO) was initially identified as a muscle relaxation factor, mediating its effects on smooth
muscle by coordinating the heme moiety of guanylate cyclase, leading to enhanced production of cGMP.
Besides smooth muscle relaxation, NO also influences a variety of biological systems including cell
proliferation, apoptosis, neurotoxicity, Parkinson disease, extracellular matrix remodeling. Many of its
effects are mediated through protein nitrosylation.
Peroxynitrite (ONOO–) is formed in the chemical reaction between nitric oxide and superoxide. ONOO–
nitrates free tyrosine and tyrosine residues in proteins; modifications that are used as markers of ONOO–
action under conditions of cellular damage and in numerous diseases.
This control is manufactured by nitration of bovine serum albumin in vitro using peroxynitrite as the NO
donor.