TNFSF10 monoclonal antibody, clone 2E5
產品名稱: TNFSF10 monoclonal antibody, clone 2E5
英文名稱: TNFSF10 monoclonal antibody, clone 2E5
產品編號: MAB0927
產品價格: null
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍:
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant TNFSF10.
- Immunogen:
- Recombinant protein corresponding to amino acids 95-281 of human TNFSF10.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1
- Storage Buffer:
- In PBS, pH 7.4
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 8743
- Gene Name:
- TNFSF10
- Gene Alias:
- APO2L,Apo-2L,CD253,TL2,TRAIL
- Gene Description:
- tumor necrosis factor (ligand) superfamily, member 10
- Omim ID:
- 603598
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. [provided by RefSeq
- Other Designations:
- Apo-2 ligand,TNF-related apoptosis inducing ligand TRAIL,tumor necrosis factor (ligand) family, member 10,tumor necrosis factor apoptosis-inducing ligand splice variant delta
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