美國 200-04 Recombinant Human IL-4 Peprotech
產品名稱： 美國 200-04 Recombinant Human IL-4 Peprotech
英文名稱： Recombinant Human IL-4
產品編號： 200-04
產品價格： 0
產品產地： 美國
品牌商標： Peprotech
更新時間： null
使用范圍： null
北京雅安達生物技術有限公司
- 聯系人 :
- 地址 : 北京市海淀區清河龍崗路51號院乾通天商務樓
- 郵編 :
- 所在區域 : 北京
- 電話 : 134****5491 點擊查看
- 傳真 : 點擊查看
- 郵箱 : 774226171@qq.com
Recombinant Human IL-4
產品編號:
200-04
別名:
BCGF,BCDF,B cell stimulating factor （BSF-1）
描述:
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
氨基酸序列:
MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
研究領域:
原產國:
USA
僅用于研究。不適用于診斷或治療。