美國(guó) 200-04 Recombinant Human IL-4 Peprotech
產(chǎn)品名稱： 美國(guó) 200-04 Recombinant Human IL-4 Peprotech
英文名稱： Recombinant Human IL-4
產(chǎn)品編號(hào)： 200-04
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 美國(guó)
品牌商標(biāo)： Peprotech
更新時(shí)間： null
使用范圍： null
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Recombinant Human IL-4
產(chǎn)品編號(hào):
200-04
別名:
BCGF,BCDF,B cell stimulating factor （BSF-1）
描述:
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant human IL-4 is a 14.9 kDa globular protein containing 129 amino acid residues.
氨基酸序列:
MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS
來源:
E.coli
純度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
The ED50 as determined by the dose-dependent stimulation of human TF-1 cells is ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
研究領(lǐng)域:
原產(chǎn)國(guó):
USA
僅用于研究。不適用于診斷或治療。