PADI4 polyclonal antibody
產品名稱： PADI4 polyclonal antibody
英文名稱： PADI4 polyclonal antibody
產品編號： PAB2519
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of PADI4.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PADI4.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Comparison of enzymatic properties between hPADI2 and hPADI4.
Nakayama-Hamada M, Suzuki A, Kubota K, Takazawa T, Ohsaka M, Kawaida R, Ono M, Kasuya A, Furukawa H, Yamada R, Yamamoto K.Biochem Biophys Res Commun. 2005 Feb 4;327(1):192-200.
- 2.
- Human PAD4 regulates histone arginine methylation levels via demethylimination.
Wang Y, Wysocka J, Sayegh J, Lee YH, Perlin JR, Leonelli L, Sonbuchner LS, McDonald CH, Cook RG, Dou Y, Roeder RG, Clarke S, Stallcup MR, Allis CD, Coonrod SA.Science. 2004 Oct 8;306(5694):279-83. Epub 2004 Sep 2.
- 3.
- A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population.
Barton A, Bowes J, Eyre S, Spreckley K, Hinks A, John S, Worthington J.Arthritis Rheum. 2004 Apr;50(4):1117-21.
- Entrez GeneID:
- 23569
- Protein Accession#:
- NP_036519;Q9UM07
- Gene Name:
- PADI4
- Gene Alias:
- PAD,PAD4,PADI5,PDI4,PDI5
- Gene Description:
- peptidyl arginine deiminase, type IV
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq
- Other Designations:
- HL-60 PAD,OTTHUMP00000002482,PADI-H protein,peptidyl arginine deiminase, type V,protein-arginine deiminase
- Related Disease
- Arthritis
- Arthritis, Rheumatoid
- Asthma
- Autoimmune Diseases
- Carcinoma, Basal Cell
- Carcinoma, Squamous Cell
- Chronic Disease
- Colitis, Ulcerative
- Crohn Disease
- Crohn's disease
- Diabetes Mellitus, Type 1
- Disease Progression
- Disease Susceptibility
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Immune System Diseases
- Malignant melanoma
- Melanoma
- Multiple Sclerosis