FLT3 monoclonal antibody, clone BV10A4 (PE)-抗體-抗體-生物在線

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亞諾法生技股份有限公司（Abnova)
FLT3 monoclonal antibody, clone BV10A4 (PE)

FLT3 monoclonal antibody, clone BV10A4 (PE)

商家詢價

產品名稱： FLT3 monoclonal antibody, clone BV10A4 (PE)

英文名稱： FLT3 monoclonal antibody, clone BV10A4 (PE)

產品編號： MAB9800

產品價格： null

產品產地： 臺灣

品牌商標： Abnova

更新時間： null

使用范圍：

亞諾法生技股份有限公司（Abnova)
  • 聯系人 :
  • 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
  • 郵編 : 11493
  • 所在區域 : 臺灣
  • 電話 : +886-920**1152 點擊查看
  • 傳真 : 點擊查看
  • 郵箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native FLT3.
  • Immunogen:
  • Native purified FLT3 from BV-173 leukemic cell line.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 130-160
  • Reactivity:
  • Human
  • Specificity:
  • The mouse monoclonal antibody BV10A4 (BV10) reacts with FLT3 (CD135), a 130-160 kDa type III receptor tyrosine kinase that is involved in early steps of hematopoiesis.
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Purification:
  • Size-exclusion chromatography purification
  • Isotype:
  • IgG1
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% BSA, 15 mM sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Avoid prolonged exposure to light. Do not freeze.
  • Recommend Usage:
  • Flow Cytometry (20 uL reagent/100 uL of whole blood or 106 cells)
    The optimal working dilution should be determined by the end user.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 2322
  • Gene Name:
  • FLT3
  • Gene Alias:
  • CD135,FLK2,STK1
  • Gene Description:
  • fms-related tyrosine kinase 3
  • Gene Summary:
  • This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq
  • Other Designations:
  • CD135 antigen,FL cytokine receptor,FLT3 receptor tyrosine kinase,OTTHUMP00000042340,fetal liver kinase 2,growth factor receptor tyrosine kinase type III,stem cell tyrosine kinase 1,tyrosine-protein kinase receptor FLT3

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