CAPTO adhere
產品名稱： CAPTO adhere
英文名稱： CAPTO adhere
產品編號： 17-5444-10
產品價格： 0
產品產地： 美國
品牌商標： GE
更新時間： null
使用范圍： null
上海基星生物科技有限公司
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- 郵編 : 201900
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| 17-5444-10 | CAPTO adhere 25 ML |
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| 17-5470-02 | Capto Q ImpRes, 100 mL |
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| 28-4024-01 | PLASMIDSELECT XTRA 25ML |
| 28-4024-02 | PLASMIDSELECT XTRA 200ML |
| 28-9032-30 | CAPTO ViralQ, 25 ML |
| 28-9032-31 | CAPTO ViralQ, 100 ML |
| 17-0420-01 | THIOPROPYL SEPHAROSE 6 B?? 15 |
| 17-0430-01 | CNBR ACTIVATED SEPHAROSE 4B?1 |
| 17-0440-01 | CON-A SEPHAROSE 4B?? 100 ML |
| 17-0440-03 | CON-A SEPHAROSE 4B?? 5 ML |
| 17-0444-01 | LENTIL LECTIN-SEPHAROSE 4 B 25 |
| 17-0467-01 | HEPARIN-SEPHAROSE CL-6B?? 10 G |
| 17-0480-01 | EPOXY ACTIVATED SEPHAROSE 6B |
| 17-0490-01 | ACTIVATED CH SEPHAROSE 4B?? 15 |
| 17-0529-01 | CALMODULIN-SEPHAROSE 4B,?10 M |
| 17-0568-01 | BENZAMIDINE-SEPHAROSE 6B |
| 17-0569-01 | EAH-SEPHAROSE 4B,?50 ML |
| 17-0571-01 | ECH-SEPHAROSE 4B,?50 ML |
| 17-0575-01 | CHELATING SEPHAROSE FAST FLOW |
| 17-0618-01 | PROTEIN G SEPHAROSE 4 FF, 5 ML |
| 17-0618-02 | PROTEIN G SEPHAROSE 4 FF, 25 M |
| 17-0618-05 | PROTEIN G SEPHAROSE 4FF 200 ML |
| 17-0640-01 | ACT THIOL SEPHAROSE 4B 15 G |
| 17-0690-01 | LYSINE-SEPHAROSE 4B?15 G |
| 17-0700-01 | 2',5' ADP-SEPHAROSE 4B?? 5 G |
| 17-0756-01 | GLUTATHIONE SEPHAROSE 4B?10 M |
| 17-0756-04 | GLUTATHIONE SEPHAROSE 4B, 300 |
| 17-0756-05 | GLUTATHIONE SEPHAROSE 4B, 100M |
| 17-0780-01 | PROTEIN A-SEPHAROSE CL-4B 1.5G |
| 17-0820-01 | CNBR ACTIVATED SEPHAROSE 6MB |
| 17-0885-01 | GAMMABIND G SEPHAROSE, 5 ML |
| 17-0885-02 | GAMMABIND G SEPHAROSE, 25 ML |
| 17-0885-04 | GAMMABIND G SEPHAROSE, 250 ML |
| 17-0886-01 | GAMMABIND PLUS SEPHAROSE, 5 ML |
| 17-0886-02 | GAMMABIND PLUS SEPHAROSE, 25 M |
| 17-0886-04 | GAMMABIND PLUS SEPHAROSE, 500 |
| 17-0906-01 | NHS ACT SEPHAROSE 4 FF 25 ML |
Capto adhere/HiTrap Capto adhere
- Contaminant removal to formulation levels in post protein A purification
- Prepacked HiTrap columns for easy screening and convenient process development.
- High capacity and productivity in flow-through mode
- Wide operational window of pH and conductivity
- Savings in time and operating costs with a two-step chromatographic process
Capto adhere/HiTrap Capto adhere
Technical Information
)
Capto adhere is a strong anion exchanger with multimodal functionality. The multimodal functionality gives a different selectivity compared to traditional anion exchangers. Capto adhere is designed for post Protein A purification of monoclonal antibodies. Removal of leached Protein A, aggregates, host cell proteins, nucleic acids and viruses from monoclonal antibodies is performed in flow-through mode at which the antibodies pass directly through the column while the contaminants are adsorbed. For best performance of Capto adhere, screening/optimization of loading conditions are required.
?
| TECHNICAL SPECIFICATIONS - Capto? adhere | |
| Ion exchanger type? | Multimodal strong anion exchanger? |
| Ionic capacity ? | 0.09 to 0.12 mmol Cl-/ml medium? |
| Average particle size1? | 75 μm (d50V)? |
| Matrix? | Highly cross-linked agarose? |
| Flow velocity2? | At least 600 cm/h in a 1-m diameter column with 20-cm bed height at 20°C using process buffers with the same viscosity as water at < 3 bar (0.3 MPa)? |
| pH-stability3? | 2 to 14 (short term) 3 to 12 (long term)? |
| Working temperature4? | 4°C to 30°C? |
| Chemical stability5? | All commonly used aqueous buffers, 1 M acetic acid, 1 M sodium hydroxide? |
| Avoid? | Oxidizing agents, anionic detergents? |
| Storage? | 20% ethanol? |
| Storage temperature? | 4°C to 30°C? |
| 1 d50v is the median particle size of the cumulative volume distribution. 2 The capacity for selective removal of some key contaminants may decrease at high flow velocity. 3 Short term pH: pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place. Long term pH: pH interval where the medium can be operated without significant change in function. 4 Capto adhere can be used under cold-room conditions, but the capacity for some key contaminants may decrease. 5 No significant change in ionic binding capacity and carbon content after one week storage in 1 M NaOH at 40°C. ? |
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http://www.gelifesciences.com/aptrix/upp01077.nsf/Content/Products?OpenDocument&moduleid=166913