GRM2 polyclonal antibody
產(chǎn)品名稱： GRM2 polyclonal antibody
英文名稱： GRM2 polyclonal antibody
產(chǎn)品編號(hào)： PAB16412
產(chǎn)品價(jià)格： null
產(chǎn)品產(chǎn)地： 臺(tái)灣
品牌商標(biāo)： Abnova
更新時(shí)間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯(lián)系人 :
- 地址 : 臺(tái)灣臺(tái)北市內(nèi)湖區(qū)洲子街 108 號(hào) 9 樓
- 郵編 : 11493
- 所在區(qū)域 : 臺(tái)灣
- 電話 : +886-920**1152 點(diǎn)擊查看
- 傳真 : 點(diǎn)擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of GRM2.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to human GRM2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Specificity:
- N-terminal extracellular domain of human.
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In PBS (0.1% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 2912
- Protein Accession#:
- Q14416
- Gene Name:
- GRM2
- Gene Alias:
- GLUR2,GPRC1B,MGLUR2,mGlu2
- Gene Description:
- glutamate receptor, metabotropic 2
- Omim ID:
- 604099
- Gene Ontology:
- Hyperlink
- Gene Summary:
- L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- glutamate metabotropic receptor 2,glutamate receptor homolog
- Gene Pathway