FGFR3/CEN4p FISH Probe
產品名稱: FGFR3/CEN4p FISH Probe
英文名稱: FGFR3/CEN4p FISH Probe
產品編號: FG0050
產品價格: 0
產品產地: 臺灣
品牌商標: Abnova
更新時間: null
使用范圍: null
亞諾法生技股份有限公司(Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.

- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
Hybridization position of the probes on the chromosome.-

- Probe 1:
????Size:
????Fluorophore:
????Location: - FGFR3
Approximately 400kb
Texas Red
4p16.3
- Probe 2:
????Size:
????Fluorophore:
????Location: - CEN4q
Approximately 650kb
FITC
4q13
- Probe Gap:
- The gap between two probes is approximately 55,800 kb
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

enlarge this image- Huma lung, adenosquamous cell carcinoma (FFPE) stained with FGFR3/CEN4p FISH Probe. Human lung, adenosquamous cell carcinoma showed no FGFR3 gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)

- enlarge
- Entrez GeneID:
- 2261
- Gene Name:
- FGFR3
- Gene Alias:
- ACH,CD333,CEK2,HSFGFR3EX,JTK4
- Gene Description:
- fibroblast growth factor receptor 3
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq
- Other Designations:
- OTTHUMP00000149959,achondroplasia, thanatophoric dwarfism,hydroxyaryl-protein kinase,tyrosine kinase JTK4
- Related Disease
- Achondroplasia
- Achondroplasia
- Alzheimer Disease
- Alzheimer disease
- Carcinoma
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Cardiovascular Diseases
- Cheilitis
- Chromosome Aberrations
- Chromosome Deletion
- Cleft Lip
- Cleft Palate
- Colon cancer
- Colonic Neoplasms
- Craniosynostoses
- Diabetes Complications
- Disease Progression
- Genetic Diseases, Inborn
