Recombinant Human HMGB1 (C-6His)
產(chǎn)品名稱： Recombinant Human HMGB1 (C-6His)
英文名稱：
產(chǎn)品編號(hào)： C357
產(chǎn)品價(jià)格： 0
產(chǎn)品產(chǎn)地： 中國
品牌商標(biāo)： Novoprotein
更新時(shí)間： null
使用范圍： null
蘇州近岸蛋白質(zhì)科技股份有限公司
- 聯(lián)系人 : 蘇州近岸蛋白質(zhì)科技股份有限公司
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High mobility group protein B1 is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus. As a nuclear protein, HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival. Meanwhile, it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte, T cell, dendritic cell activities in inflammatory responses.