Recombinant Biotinylated Human CD276(B7H3 4Ig) Protein,His-Avi Tag
產品名稱： Recombinant Biotinylated Human CD276(B7H3 4Ig) Protein,His-Avi Tag
英文名稱： Recombinant Biotinylated Human CD276(B7H3 4Ig) Protein,His-Avi Tag
產品編號： 94003ES
產品價格： 詢價
產品產地： Yeasen
品牌商標： Yeasen
更新時間： 2026-02-10T16:51:47
使用范圍： null
翌圣生物科技（上海）股份有限公司
- 聯系人 : 李自轉
- 地址 : 上海市浦東新區天雄路166弄一號樓三層南單元
- 郵編 : 200030
- 所在區域 : 上海
- 電話 : 139****5640 點擊查看
- 傳真 : 點擊查看
- 郵箱 : lizizhuan@yeasen.com
- 二維碼 : 點擊查看
產品介紹
B7H3, also known as CD276, is a protein belonging to the B7 family of immune regulatory molecules. It is a transmembrane protein that plays a significant role in immune regulation and tumor immunotherapy. B7H3 can exist in different structural forms, with variations such as 4IG (containing 4 immunoglobulin domains) and 2IG (containing 2 immunoglobulin domains).
This protein is known to be highly expressed in various tumors and is closely associated with tumor development, progression, and prognosis. In the context of tumor immunotherapy, B7H3 serves as an important target due to its ability to modulate T cell responses. Inhibiting B7H3 protein can enhance the killing capacity of T cells against tumor cells, thereby improving the effectiveness of cancer treatment.
Overall, B7H3 plays a crucial role in immune regulation, immune response modulation, and tumor immune evasion. Understanding the mechanisms involving B7H3 protein can provide valuable insights into immunotherapy strategies and tumor development.
產品性質
|
產品別稱
|
4Ig-B7-H3,B7-H3,CD276,PSEC0249,UNQ309,PRO352,B7 homolog 3
|
|
種屬
|
Human
|
|
表達序列
|
Gly 27 - Thr 461
|
|
Accession
|
Q5ZPR3-1
|
|
標簽
|
C-His-Avi Tag
|
|
表達系統
|
HEK293
|
|
分子量
|
The protein has a predicted MW of 50.2 kDa
|
|
純度
|
> 95% as determined by SDS-PAGE
|
|
內毒素
|
< 1.0 EU per μg by the LAL method.
|
|
制劑
|
Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
|
|
外觀
|
Liquid
|
|
生物活性
|
Human Activin B Protein; His Tag was added into Activin A Reporter Cell Line and stimulates signals.
|
產品特色
高純度、高活性、低內毒素、高批間一致性
應用案例
SDS-PAGE
Figure 1.On SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Bioactivity-ELISA
Figure 2. Biotinylated Human CD276(B7H3 4Ig) Protei, His-Avi Tag was immobilized at 1 μg/ml (100 μL/well) on streptavidin precoated. Increasing concentrations of Anti-CD276(B7H3) hIgG1 Reference Antibody were added.
存儲條件
-85 ~ -65℃保存，收到貨之日起，6個月有效期。避免反復凍融，建議等分分裝為一次實驗使用量，分裝后，-80℃凍存。