NOD2 monoclonal antibody, clone 2D9
產品名稱： NOD2 monoclonal antibody, clone 2D9
英文名稱： NOD2 monoclonal antibody, clone 2D9
產品編號： MAB2303
產品價格： null
產品產地： 臺灣
品牌商標： Abnova
更新時間： null
使用范圍：
亞諾法生技股份有限公司（Abnova)
- 聯系人 :
- 地址 : 臺灣臺北市內湖區洲子街 108 號 9 樓
- 郵編 : 11493
- 所在區域 : 臺灣
- 電話 : +886-920**1152 點擊查看
- 傳真 : 點擊查看
- 郵箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant NOD2.
- Immunogen:
- Recombinant protein corresponding to amino acids 28-301 of human NOD2.
- Host:
- Mouse
- Reactivity:
- Human, Primates
- Specificity:
- This antibody is specific to NOD2 protein.
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In Tris-glycine, 150 mM NaCl
- Storage Instruction:
- Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Publication Reference
- 1.
- Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis.
Ogura Y, Lala S, Xin W, Smith E, Dowds TA, Chen FF, Zimmermann E, Tretiakova M, Cho JH, Hart J, Greenson JK, Keshav S, Nunez G.Gut. 2003 Nov;52(11):1591-7.
- 2.
- Crohn's disease and the NOD2 gene: a role for paneth cells.
Lala S, Ogura Y, Osborne C, Hor SY, Bromfield A, Davies S, Ogunbiyi O, Nunez G, Keshav S.Gastroenterology. 2003 Jul;125(1):47-57.
- Applications
- Western Blot (Cell lysate)
- Western blot analysis of NOD2 in 50 ug of HT-29 cell lysate with NOD2 monoclonal antibody, clone 2D9 (Cat # MAB2303).
- Entrez GeneID:
- 64127
- Gene Name:
- NOD2
- Gene Alias:
- ACUG,BLAU,CARD15,CD,CLR16.3,IBD1,NLRC2,NOD2B,PSORAS1
- Gene Description:
- nucleotide-binding oligomerization domain containing 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. [provided by RefSeq
- Other Designations:
- NLR family, CARD domain containing 2,NOD-like receptor C2,OTTHUMP00000164224,caspase recruitment domain family, member 15,caspase recruitment domain protein 15,inflammatory bowel disease protein 1,nucleotide-binding oligomerization domain 2,nucleotide-bin
- Related Disease
- Abscess
- Acquired Hyperostosis Syndrome
- Acute Disease
- Adenocarcinoma
- Anus Diseases
- Arthritis
- Arthritis, Juvenile Rheumatoid
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Arthropathy, Neurogenic
- Asthma
- Asthma
- Atherosclerosis
- Atherosclerosis
- Atrial Fibrillation
- Autoimmune Diseases
- Bacteremia
- Bacterial Infections
- Behcet Syndrome